Dermatitis Herpetiformis- its Presentation and Management
نویسندگان
چکیده
منابع مشابه
Dermatitis herpetiformis.
Dermatitis herpetiformis (DH) is an autoimmune, pleiomorphic, papulovesicular disorder associated with celiac disease and gluten sensitivity. DH is characterized by subepidermal bullae on hematoxylin and eosin staining and granular immunoglobulin A deposits in the dermal papillae using the direct immunofluorescence method. Antibodies to tissue transglutaminase and epidermal transgulatminase can...
متن کاملDermatitis herpetiformis: pathophysiology, clinical presentation, diagnosis and treatment*
Researches on DH have shown that it is not just a bullous skin disease, but a cutaneous-intestinal disorder caused by hypersensitivity to gluten. Exposure to gluten is the starting point of an inflammatory cascade capable of forming autoantibodies that are brought to the skin, where they are deposited, culminating in the formation of skin lesions. These lesions are vesico-bullous, pruritic, and...
متن کاملDermatitis herpetiformis and vitiligo.
Dermatitis herpetiformis (DH) is a rare immunobullous disorder of the skin that is associated with gluten hypersensitivity. Subepidermal IgA-type antibody deposition against tissue transglutaminase leads to dense neutrophilic microabscess and eventually into vesicles in dermal papillae, which may occasionally merge into bullae. Being a subepidermal vesiculobullous disorder, DH is frequently ass...
متن کاملDermatitis herpetiformis.
Dermatitis herpetiformis (DH), described over 100 years ago, is a life-long blistering skin disease that can appear at any age. Dapsone controls the rash effectively and has been used for over 50 years in the treatment of DH. Major landmark in the research of DH was 30 years ago the discovery of granular IgA deposits in the upper papillary dermis,1 and further differentiation of an autoimmune d...
متن کاملReview: dermatitis herpetiformis*
Dermatitis herpetiformis (DH) or Duhring-Brocq disease is a chronic bullous disease characterized by intense itching and burning sensation in the erythematous papules and urticarial plaques, grouped vesicles with centrifuge growth, and tense blisters. There is an association with the genotypes HLA DR3, HLA DQw2, found in 80-90% of cases. It is an IgA-mediated cutaneous disease, with immunoglobu...
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ژورنال
عنوان ژورنال: TAJ: Journal of Teachers Association
سال: 1970
ISSN: 2408-8854,1019-8555
DOI: 10.3329/taj.v22i1.5044